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pentobarbital will reduce the level or effect of pimozide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.pentobarbital raises effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Caution/Keep track of. Coadministration of ifosfamide with CYP2B6 inducers may raise metabolism of ifosfamid